To solve this problem, we need to analyze each statement regarding skeletal muscle:$\newline \bullet$A. Muscle bundles are held together by collagenous connective tissue layer called fascicle.$\newline$ - This statement is incorrect. The term "fascicle" refers to a bundle of muscle fibers, not the connective tissue. The connective tissue that holds muscle bundles together is called the "epimysium."$\newline \bullet$B. Sarcoplasmic reticulum of muscle fibre is a storehouse of calcium ions.$\newline$ - This statement is correct. The sarcoplasmic reticulum is an organelle in muscle cells that stores calcium ions, which are essential for muscle contraction.$\newline \bullet$C. Striated appearance of skeletal muscle fibre is due to the distribution pattern of actin and myosin proteins.$\newline$ - This statement is correct. The striated appearance of skeletal muscle fibers is due to the alternating pattern of actin (thin filaments) and myosin (thick filaments) within the myofibrils.$\newline \bullet$D. M line is considered as the functional unit of contraction called sarcomere.$\newline$ - This statement is incorrect. The sarcomere is the functional unit of contraction in a muscle fiber, but it is defined as the segment between two Z lines, not the M line. The M line is located in the center of the sarcomere.$\newline$Based on the analysis, the correct statements are B and C.$\newline$Therefore, the most appropriate answer is Option 2: B and C only.